Influence of age and time interval between death and autopsy on dopamine and 3-methoxytyramine levels in human basal ganglia

J Neural Transm. 1976;38(3-4):271-6. doi: 10.1007/BF01249444.


The caudate nuclei and putamens of 30 human brains were analyzed for dopamine and its metabolite 3-methoxytyramine, most of which was presumably formed from dopamine postmortally. It was found that dopamine and the sum (dopamine + methoxytyramine) but not methoxytyramine declined with the time interval between death and autopsy as well as with age.

MeSH terms

  • Age Factors
  • Basal Ganglia / analysis*
  • Caudate Nucleus / analysis
  • Dopamine / analysis*
  • Humans
  • Postmortem Changes
  • Putamen / analysis
  • Time Factors
  • Tyramine / analogs & derivatives
  • Tyramine / analysis*


  • Dopamine
  • Tyramine