Neural progenitors and stem cells: mechanisms of progenitor heterogeneity

Curr Opin Neurobiol. 1998 Feb;8(1):37-44. doi: 10.1016/s0959-4388(98)80006-8.


Heterogeneity among progenitor cells in the vertebrate nervous system has been documented with increasing frequency over the past few years. It has become clear that differences in progenitor cells help to determine when and how they respond to environmental signals. More recent studies have begun to elucidate the molecular basis of the differences in progenitor cell subpopulations that control their developmental potential and responsiveness to environmental signals.

Publication types

  • Review

MeSH terms

  • Animals
  • Cell Lineage / physiology
  • Female
  • Humans
  • Nervous System / cytology
  • Nervous System / embryology*
  • Nervous System / growth & development*
  • Neurons / physiology*
  • Pregnancy
  • Stem Cells / physiology*