Axon Guidance to and From Choice Points

Curr Opin Neurobiol. 1998 Feb;8(1):64-72. doi: 10.1016/s0959-4388(98)80009-3.

Abstract

Significant progress has been made recently in understanding axon guidance to and from choice points. Netrins have been shown to function as conserved midline chemoattractants in vertebrates and insects, and receptors for netrins and semaphorins/collapsins have been identified. More evidence has accumulated that repulsion plays a key role in guidance, including the involvement of the ephrin/Eph receptor system in contact repulsion.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Axons / physiology*
  • Brain / cytology*
  • Brain / growth & development*
  • Female
  • Humans
  • Nerve Tissue Proteins / physiology*
  • Pregnancy

Substances

  • Nerve Tissue Proteins