Metastases to parotid gland from cancers of the upper airway and digestive tract

Br J Oral Maxillofac Surg. 1998 Feb;36(1):54-7. doi: 10.1016/s0266-4356(98)90750-1.

Abstract

Forty-four cases of parotid metastases were diagnosed and treated in the period 1968-1994. In 10 patients (23%), the primary tumour was sited in the mucosal layer of the upper airway or digestive tract: oropharynx (n=3), larynx (n=3), nasopharynx (n=2), hypopharynx (n=1) and the maxillary sinus (n=1). Histologically, the primary tumour was squamous cell carcinoma in 9 cases and adenocarcinoma in one. One patient received surgical treatment only, two patients surgery and postoperative radiotherapy, one radiotherapy only, four chemotherapy and two symptomatic treatment only. Only one patient is alive, disease-free, 5 years after treatment. The other patients died: six within 1 year, two within 2 years and one within 3 years of diagnosis.

MeSH terms

  • Adenocarcinoma / pathology
  • Adenocarcinoma / secondary
  • Aged
  • Antineoplastic Agents / therapeutic use
  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / secondary
  • Disease-Free Survival
  • Follow-Up Studies
  • Humans
  • Laryngeal Neoplasms / pathology*
  • Lymphatic Metastasis / pathology
  • Magnetic Resonance Imaging
  • Male
  • Maxillary Sinus Neoplasms / pathology*
  • Middle Aged
  • Parotid Neoplasms / diagnosis
  • Parotid Neoplasms / drug therapy
  • Parotid Neoplasms / radiotherapy
  • Parotid Neoplasms / secondary*
  • Parotid Neoplasms / surgery
  • Pharyngeal Neoplasms / pathology*
  • Radiotherapy, Adjuvant
  • Sialography
  • Survival Rate
  • Tomography, X-Ray Computed

Substances

  • Antineoplastic Agents