Hydatidiform mole with non-metastatic pulmonary complications and a false low level of hCG

Eur J Obstet Gynecol Reprod Biol. 1998 Apr;77(2):235-7. doi: 10.1016/s0301-2115(97)00268-6.

Abstract

We present a case of hydatidiform mole with non-metastatic pulmonary complications and stress that termination of the pregnancy will cure the patient. The frequent use of sonography in early pregnancy makes it possible to diagnose pathological pregnancies earlier than was possible before. The fact that molar pregnancies are now being terminated at an earlier stage means that some of the complications associated with advanced moles are seldom encountered today. The case also illustrates the so-called 'high dose hook effect' meaning that an extremely high level of hCG may falsely be reported to be very low by the laboratory.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Chorionic Gonadotropin / blood*
  • False Negative Reactions
  • Female
  • Humans
  • Hydatidiform Mole / blood
  • Hydatidiform Mole / complications
  • Hydatidiform Mole / diagnosis*
  • Lung Diseases / etiology*
  • Methotrexate / therapeutic use
  • Pregnancy
  • Uterine Neoplasms / blood
  • Uterine Neoplasms / complications
  • Uterine Neoplasms / diagnosis*

Substances

  • Chorionic Gonadotropin
  • Methotrexate