Lambda repressor regulates the switch between PR and Prm promoters

Nature. 1976 Aug 19;262(5570):665-9. doi: 10.1038/262665a0.

Abstract

The DNA region containing the Or operator, Pr and Prm promoters and their transcription initiations is sequenced. By binding to Or, repressor turns off Pr, turns on Prm and at higher concentrations turns off Prm, regulating its own synthesis. Prm mRNA is unique in beginning immediately with the initiation of translation, without a preceding leader sequence.

MeSH terms

  • Base Sequence
  • Codon
  • Coliphages / metabolism*
  • DNA, Viral / analysis
  • Genes*
  • Genes, Regulator*
  • Peptide Chain Initiation, Translational
  • RNA, Messenger / analysis
  • RNA, Messenger / biosynthesis*
  • RNA, Viral / analysis
  • RNA, Viral / biosynthesis
  • Transcription, Genetic*
  • Viral Proteins / biosynthesis*

Substances

  • Codon
  • DNA, Viral
  • RNA, Messenger
  • RNA, Viral
  • Viral Proteins

Associated data

  • GENBANK/J02459
  • GENBANK/M17233