Neuroaugmentation in the treatment of complex regional pain syndrome of the upper extremity

Acta Orthop Belg. 1998 Mar;64(1):57-63.


The authors report their results on 36 patients with advanced stages of complex regional pain syndrome. They were treated with either spinal cord stimulation, or peripheral nerve stimulation, and in some cases with both modalities. Thirty six months after implantation the reported pain measured on visual analogue scales was an average of 53% better, this change was statistically significant. Analgesic consumption decreased by about 50% or was reportedly more effective. The authors conclude that in late stages of complex regional pain syndrome, neuroaugmentation is a reasonable option when alternative therapies have failed.

MeSH terms

  • Adult
  • Analgesics, Opioid / administration & dosage
  • Analgesics, Opioid / therapeutic use
  • Arm / innervation*
  • Combined Modality Therapy
  • Electric Stimulation Therapy* / instrumentation
  • Electric Stimulation Therapy* / methods
  • Electrodes, Implanted
  • Female
  • Follow-Up Studies
  • Humans
  • Longitudinal Studies
  • Male
  • Median Nerve / physiopathology
  • Middle Aged
  • Nerve Block
  • Pain Measurement
  • Radial Nerve / physiopathology
  • Reflex Sympathetic Dystrophy / drug therapy
  • Reflex Sympathetic Dystrophy / physiopathology
  • Reflex Sympathetic Dystrophy / therapy*
  • Spinal Cord / physiopathology
  • Stellate Ganglion / physiopathology
  • Syndrome
  • Ulnar Nerve / physiopathology


  • Analgesics, Opioid