Regeneration of ascending spinal axons in goldfish

Brain Res. 1998 Apr 27;791(1-2):235-45. doi: 10.1016/s0006-8993(98)00105-x.

Abstract

Regeneration of descending spinal cord tracts occur spontaneously in adult goldfish. Very little information is available regarding the fate of ascending fibers. Using Dextran amines as a tracer, we studied the normal and regenerated ascending axonal projection patterns in adult goldfish brain nuclei. Present study includes spinal projections to torus semicircularis, hypothalamus, thalamus and the telencephalon. Regenerated fibers had finer caliber axons and the terminal axonal arbors covered a larger area than the corresponding normal ones.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Afferent Pathways / physiology
  • Animals
  • Axons / physiology*
  • Biotin / analogs & derivatives
  • Brain Mapping*
  • Dextrans
  • Diencephalon / physiology
  • Fluorescent Dyes
  • Goldfish / physiology*
  • Mesencephalon / physiology
  • Nerve Regeneration / physiology*
  • Spinal Cord / physiology*
  • Spinal Cord / ultrastructure
  • Telencephalon / physiology

Substances

  • Dextrans
  • Fluorescent Dyes
  • biotinylated dextran amine
  • Biotin