How should we treat tophaceous gout in patients with allopurinol hypersensitivity?

Adv Exp Med Biol. 1998:431:19-23. doi: 10.1007/978-1-4615-5381-6_4.

Abstract

We studied purine metabolism in gouty patients from three categories: primary gout, familial juvenile hyperuricaemic nephropathy (FJHN) and partial HPRT deficiency.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Allopurinol / adverse effects*
  • Benzbromarone / therapeutic use
  • Creatinine / blood
  • Drug Hypersensitivity*
  • Gout / blood
  • Gout / drug therapy
  • Gout / therapy*
  • Gout Suppressants / adverse effects
  • Gout Suppressants / therapeutic use*
  • Humans
  • Hypoxanthine Phosphoribosyltransferase / deficiency
  • Kidney Failure, Chronic / complications
  • Male
  • Middle Aged
  • Purine-Pyrimidine Metabolism, Inborn Errors / therapy*
  • Uric Acid / blood

Substances

  • Gout Suppressants
  • Uric Acid
  • Benzbromarone
  • Allopurinol
  • Creatinine
  • Hypoxanthine Phosphoribosyltransferase