Purine nucleoside phosphorylase deficient mice exhibit both an age dependent attrition of thymocytes and impaired thymocyte differentiation

Adv Exp Med Biol. 1998:431:515-8. doi: 10.1007/978-1-4615-5381-6_100.

Authors

F F Snyder¹, J P Jenuth, E R Mably, R K Mangat, A Pinto-Rojas

Affiliation

¹ Department of Medical Genetics, Faculty of Medicine, University of Calgary, Alberta, Canada.

PMID: 9598120
DOI: 10.1007/978-1-4615-5381-6_100

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aging / immunology
Alleles
Animals
Cell Differentiation
Mice
Mice, Inbred C57BL
Mice, Mutant Strains
Point Mutation*
Purine-Nucleoside Phosphorylase / deficiency*
Purine-Nucleoside Phosphorylase / genetics*
Spleen / immunology
T-Lymphocytes / cytology
T-Lymphocytes / immunology*
Thymus Gland / growth & development
Thymus Gland / immunology*

Substances

Purine-Nucleoside Phosphorylase