Induction of in vivo resistance against gemcitabine (dFdC, 2',2'-difluoro-deoxycytidine)

Adv Exp Med Biol. 1998;431:637-40. doi: 10.1007/978-1-4615-5381-6_123.
No abstract available

MeSH terms

  • Animals
  • Antimetabolites, Antineoplastic / therapeutic use*
  • Antimetabolites, Antineoplastic / toxicity*
  • Cell Line
  • Colonic Neoplasms / drug therapy*
  • Deoxycytidine / analogs & derivatives*
  • Deoxycytidine / therapeutic use
  • Deoxycytidine / toxicity
  • Deoxycytidine Kinase / metabolism
  • Drug Resistance, Neoplasm*
  • Kinetics
  • Mice
  • Mice, Inbred BALB C
  • Thymidine Kinase / metabolism
  • Tumor Cells, Cultured

Substances

  • Antimetabolites, Antineoplastic
  • Deoxycytidine
  • gemcitabine
  • thymidine kinase 2
  • Thymidine Kinase
  • thymidine kinase 1
  • Deoxycytidine Kinase