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Case Reports
. 1998 May;64(5):636-42.
doi: 10.1136/jnnp.64.5.636.

Intracranial Aneurysms in Three Patients With Disseminated Lyme Borreliosis: Cause or Chance Association?

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Free PMC article
Case Reports

Intracranial Aneurysms in Three Patients With Disseminated Lyme Borreliosis: Cause or Chance Association?

J Oksi et al. J Neurol Neurosurg Psychiatry. .
Free PMC article

Abstract

Methods: Three patients with Borrelia burgdorferi infection and intracranial aneurysms are described.

Results: All three patients had neurological symptoms. Perivascular and vasculitic lymphocytic inflammation were detected in the brain biopsy specimen of one patient. The aneurysm was located in the internal carotid arteries in two patients and in the basilar artery in one patient. The aneurysm ruptured in two patients.

Conclusions: Cerebral lymphocytic vasculitis and intracranial aneurysms may be associated with B burgdorferi infection. It is suggested that inflammatory changes caused by B burgdorferi in vessel walls may be a pathogenetic mechanism for the formation of aneurysms.

Comment in

  • Lyme borreliosis and intracranial aneurysm.
    Polet JD, Weinstein HC. Polet JD, et al. J Neurol Neurosurg Psychiatry. 1999 Jun;66(6):806-7. doi: 10.1136/jnnp.66.6.806a. J Neurol Neurosurg Psychiatry. 1999. PMID: 10400516 Free PMC article. No abstract available.

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References

    1. Dis Nerv Syst. 1976 Mar;37(3):133-6 - PubMed
    1. Am J Pathol. 1985 Jan;118(1):26-34 - PubMed
    1. Arch Neurol. 1987 Jul;44(7):781-3 - PubMed
    1. J Neurol Neurosurg Psychiatry. 1987 Dec;50(12):1703-4 - PubMed
    1. Neurology. 1988 Jun;38(6):863-7 - PubMed

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