Staphylococcal Endophthalmitis Following Cataract Extraction in a Patient With Darier's Disease

Cornea. 1998 May;17(3):335-7.


Purpose: To report staphylococcal endophthalmitis following cataract extraction in a patient with Darier' s disease.

Methods: A 67-year-old man presented with decreased visual acuity OD and hypopyon 3 days status post-cataract extraction with intraocular lens placement. The patient was hospitalized and placed on topical and intravenous antibiotics. A diagnostic vitreous tap, pars plana vitrectomy, and intravitreal antibiotic installation were performed.

Results: Vitreal tap cultures indicated Staphylococcus epidermidis. His clinical status improved after vitrectomy and antibiotic therapy. The same bacteria was cultured from the patient's eyelids.

Conclusions: The source of the S. epidermidis was the skin lesions on the patient's face and eyelids. Darier's disease is an exfoliative hyperkeratotic skin disease that affects all areas on the body except the buttocks. Although clean, sterile surgical techniques were followed, the risk of endophthalmitis following intraocular surgery in a patient with Darier's disease may be increased due to his or her dermatologic condition.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anti-Bacterial Agents
  • Cataract / complications
  • Cataract Extraction / adverse effects*
  • Darier Disease / complications*
  • Drug Administration Routes
  • Drug Therapy, Combination / therapeutic use
  • Endophthalmitis / diagnosis
  • Endophthalmitis / microbiology*
  • Endophthalmitis / therapy
  • Eye Infections, Bacterial* / diagnosis
  • Eye Infections, Bacterial* / etiology
  • Eye Infections, Bacterial* / therapy
  • Follow-Up Studies
  • Humans
  • Lens Implantation, Intraocular
  • Male
  • Postoperative Complications
  • Staphylococcal Infections / diagnosis
  • Staphylococcal Infections / microbiology*
  • Staphylococcal Infections / therapy
  • Staphylococcus epidermidis / isolation & purification*
  • Vitrectomy
  • Vitreous Body / microbiology
  • Vitreous Body / surgery


  • Anti-Bacterial Agents