A case of late-onset MELAS

Arch Neurol. 1998 May;55(5):722-5. doi: 10.1001/archneur.55.5.722.


We describe a 60-year-old man with MELAS syndrome (mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes) and discuss the mitochondrial DNA point mutation 3243. A diagnosis of MELAS should be considered in the appropriate clinical setting at any age.

Publication types

  • Case Reports

MeSH terms

  • Age of Onset
  • Humans
  • MELAS Syndrome / diagnosis*
  • MELAS Syndrome / genetics
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Point Mutation