Efficacy of cyproheptadine for nightmares associated with posttraumatic stress disorder

Compr Psychiatry. 1998 May-Jun;39(3):160-4. doi: 10.1016/s0010-440x(98)90076-1.

Abstract

A retrospective review of the psychiatric records of nine patients with posttraumatic stress disorder (PTSD) was conducted to determine the efficacy of cyproheptadine in relieving nightmares. The treatment dose was 4 to 12 mg at bedtime. The response varied from complete remission to a decrease in the intensity and frequency of nightmares.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cyproheptadine / therapeutic use*
  • Dreams / drug effects*
  • Drug Administration Schedule
  • Drug Therapy, Combination
  • Evaluation Studies as Topic
  • Female
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Serotonin Antagonists / therapeutic use*
  • Stress Disorders, Post-Traumatic / drug therapy*
  • Treatment Outcome

Substances

  • Serotonin Antagonists
  • Cyproheptadine