Intraoperative localization of small intestinal bleeding in an infant by methylene blue injection: a case report

J Pediatr Surg. 1998 May;33(5):754-5. doi: 10.1016/s0022-3468(98)90209-3.


During the evaluation of patients with profuse gastrointestinal bleeding, it is often difficult to accurately localize bleeding sites in the small intestine. Moreover, during laparotomy, there may be no intraoperative findings to allow identification and resection of the bleeding lesion. Here the authors report a case of severe intestinal bleeding in an infant in whom the intraoperative injection of methylene blue dye into a terminal branch of the superior mesenteric artery was critical in determining the exact location of bleeding. After accurate localization of the bleeding source and segmental intestinal resection, the child recovered uneventfully with no recurrence of gastrointestinal bleeding. To the authors' knowledge, this is the first reported use of this technique in infancy.

Publication types

  • Case Reports

MeSH terms

  • Angiography
  • Coloring Agents*
  • Disease-Free Survival
  • Female
  • Gastrointestinal Hemorrhage / diagnosis*
  • Gastrointestinal Hemorrhage / etiology
  • Gastrointestinal Hemorrhage / surgery
  • Humans
  • Infant, Newborn
  • Jejunal Diseases / diagnosis*
  • Jejunal Diseases / etiology
  • Jejunal Diseases / surgery
  • Laparotomy
  • Lung Diseases, Interstitial / complications
  • Lung Diseases, Interstitial / congenital
  • Lung Diseases, Interstitial / surgery
  • Lung Transplantation
  • Methylene Blue*
  • Monitoring, Intraoperative
  • Radiographic Image Enhancement / methods*
  • Sensitivity and Specificity


  • Coloring Agents
  • Methylene Blue