Recombination at work for meiosis

Curr Opin Genet Dev. 1998 Apr;8(2):200-11. doi: 10.1016/s0959-437x(98)80142-1.


In sexually reproducing organisms, homologous recombination increases genetic diversity in gametes and ensures proper chromosome segregation. Recent publications have provided details of the molecular intermediates and proteins involved, the control of the distribution of recombination events at the chromosomal level, and the surveillance mechanisms that coordinate recombination with the meiotic cell cycle.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Aneuploidy
  • Animals
  • Crossing Over, Genetic
  • DNA Damage
  • DNA Repair
  • Humans
  • Meiosis*
  • Models, Genetic
  • Recombination, Genetic*
  • Saccharomyces cerevisiae
  • Templates, Genetic