Diagnosis and treatment of renal tubular disorders

Semin Nephrol. 1998 May;18(3):317-29.


There is a wide variety of renal tubular disorders affecting children. Understanding the pathophysiology of each disease assists in the recognition and treatment of these diseases, which can have profound effects on a child's growth and development. We review some of the more common tubular disorders found in children, emphasizing those conditions in which recent advances have been made in understanding of the specific genetic or physiological defect responsible: Fanconi's syndrome, cystinuria, renal tubular acidosis, and the hypokalemic metabolic alkaloses. Current recommendations are presented for diagnosing and treating these conditions.

Publication types

  • Review

MeSH terms

  • Acidosis, Renal Tubular / diagnosis
  • Acidosis, Renal Tubular / therapy
  • Child
  • Fanconi Syndrome / diagnosis
  • Fanconi Syndrome / therapy
  • Humans
  • Kidney Diseases / diagnosis*
  • Kidney Diseases / genetics
  • Kidney Diseases / therapy*
  • Kidney Tubules*