Abstract
Research into two of the four classes of naturally produced beta-lactams--the clavams and carbapenems--has started to throw light upon their biochemical pathways and underlying genetics. Interesting similarities between these two classes, from their joint discovery to an apparently common beta-lactam ring-forming enzyme, are now being revealed.
Publication types
-
Research Support, Non-U.S. Gov't
-
Review
MeSH terms
-
Anti-Bacterial Agents / chemistry
-
Anti-Bacterial Agents / metabolism*
-
Carbapenems / chemistry
-
Carbapenems / metabolism*
-
Clavulanic Acids / chemistry
-
Clavulanic Acids / metabolism
-
beta-Lactams / chemistry
-
beta-Lactams / metabolism*
Substances
-
Anti-Bacterial Agents
-
Carbapenems
-
Clavulanic Acids
-
beta-Lactams