Common polymorphisms in genes encoding the human mineralocorticoid receptor and the human amiloride-sensitive sodium channel

J Steroid Biochem Mol Biol. 1998 Mar;64(5-6):227-30. doi: 10.1016/s0960-0760(97)00195-7.

Abstract

We have examined the human mineralocorticoid receptor gene and the genes encoding the three subunits of the human amiloride-sensitive epithelial sodium channel. Eight new common polymorphisms were identified in these genes which may be useful in genotyping and linkage analysis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amiloride / pharmacology*
  • DNA Primers / chemistry
  • European Continental Ancestry Group
  • Female
  • Genetic Linkage / genetics
  • Genotype
  • Humans
  • Kidney / physiology*
  • Male
  • Molecular Sequence Data
  • Polymorphism, Genetic / genetics*
  • Pseudohypoaldosteronism / physiopathology
  • Receptors, Mineralocorticoid / genetics*
  • Sequence Analysis, DNA
  • Sodium Channels / genetics*

Substances

  • DNA Primers
  • Receptors, Mineralocorticoid
  • Sodium Channels
  • Amiloride

Associated data

  • GENBANK/X97925
  • GENBANK/Z92978
  • GENBANK/Z92979
  • GENBANK/Z92980
  • GENBANK/Z92981