Cytologic features of granulomatous mastitis. Report of a case with fine needle aspiration cytology and immunocytochemical findings

Acta Cytol. 1998 May-Jun;42(3):716-20. doi: 10.1159/000331832.


Background: Granulomatous mastitis, a rare condition of unknown etiology, affects women of childbearing age and clinically simulates breast carcinoma.

Case: Granulomatous mastitis of the breast in a 32-year-old female was studied by fine needle aspiration cytology. Aspirated material was quite cellular and consisted of epithelioid histiocytes, lymphocytes, plasma cells, neutrophils and multinucleated Langhans-type giant cells. However, no cheesy, necrotic material in the background was noted.

Conclusion: Granulomatous mastitis, although infrequently reported, appears to have rather characteristic cellular features that may allow its recognition.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Biopsy, Needle*
  • Breast / pathology*
  • Breast Neoplasms / diagnosis
  • Diagnosis, Differential
  • Female
  • Giant Cells, Langhans / pathology
  • Granuloma / diagnosis
  • Granuloma / diagnostic imaging
  • Granuloma / pathology*
  • Granuloma / surgery
  • Humans
  • Mastitis / diagnosis
  • Mastitis / diagnostic imaging
  • Mastitis / pathology*
  • Mastitis / surgery
  • Phagocytes / pathology
  • Ultrasonography