Familial idiopathic intracranial hypertension with spinal and radicular pain

Arch Neurol. 1998 Jun;55(6):854-6. doi: 10.1001/archneur.55.6.854.


Objective: To describe a mother and her 2 sons affected by idiopathic intracranial hypertension (IIH), associated in the sons with root irritation symptom. Unlike the other 4 families reported previously, obesity was not present in our patients.

Design: Case reports.

Setting: Department of pediatrics in a university school of Medicine, Naples, Italy.

Patients: A mother (aged 36 years) and her 2 sons (aged 14 and 9 years) developed IIH at different times. Neuroimaging showed an empty sella in the mother, while IIH was associated with spinal and radicular pain in her 2 sons. The mother and the younger son developed permanent visual loss.

Conclusions: Ophthalmologic follow-up in our patients indicates that IIH is a chronic disease. Surgical treatment should be considered an option.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Female
  • Humans
  • Intracranial Hypertension / complications*
  • Intracranial Hypertension / diagnosis
  • Intracranial Hypertension / genetics*
  • Magnetic Resonance Imaging
  • Male
  • Pain / etiology*
  • Polyradiculopathy / etiology*
  • Sella Turcica / pathology
  • Spine
  • Vision Disorders / etiology