Low molecular weight heparin-induced skin necrosis occurring distant from injection sites and without thrombocytopenia

U J Tietge; H H Schmidt; E Jäckel; C Trautwein; M P Manns

doi:10.1046/j.1365-2796.1998.00304.x

Low molecular weight heparin-induced skin necrosis occurring distant from injection sites and without thrombocytopenia

J Intern Med. 1998 Apr;243(4):313-5. doi: 10.1046/j.1365-2796.1998.00304.x.

Authors

U J Tietge¹, H H Schmidt, E Jäckel, C Trautwein, M P Manns

Affiliation

¹ Department of Gastroenterology and Hepatology, Medizinische Hochschule Hannover, Germany.

PMID: 9627146
DOI: 10.1046/j.1365-2796.1998.00304.x

Abstract

In this paper we report a case of 76-year-old white male patient with skin necrosis induced by subcutaneous prophylactic administration of low-molecular-weight heparin (LMWH). Skin necrosis occurred distant from heparin injection sites and without concomitant thrombocytopenia. This is the first reported case presenting these clinical findings.

Publication types

Case Reports

MeSH terms

Aged
Fibrinolytic Agents / adverse effects*
Heparin, Low-Molecular-Weight / adverse effects*
Humans
Injections, Subcutaneous
Male
Necrosis
Skin / drug effects*
Skin / pathology*
Thrombocytopenia

Substances

Fibrinolytic Agents
Heparin, Low-Molecular-Weight