Culture-negative endocarditis caused by Bartonella henselae

J Pediatr. 1998 Jun;132(6):1051-4. doi: 10.1016/s0022-3476(98)70410-x.

Abstract

A 4-year-old girl presented with clinical evidence of infective endocarditis involving her aortic valve, but blood cultures were sterile. Serologic studies and analysis of resected valve by immunohistochemistry and polymerase chain reaction established the diagnosis of Bartonella henselae endocarditis. Clinicians should be aware that B. henselae can cause apparent culture-negative endocarditis in children.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Antibodies, Bacterial / blood
  • Aortic Valve / chemistry
  • Aortic Valve / pathology
  • Bartonella henselae / isolation & purification*
  • Cat-Scratch Disease / complications*
  • Cat-Scratch Disease / diagnosis
  • Cat-Scratch Disease / therapy
  • Child, Preschool
  • Endocarditis, Bacterial / diagnosis
  • Endocarditis, Bacterial / microbiology*
  • Endocarditis, Bacterial / surgery
  • Female
  • Heart Defects, Congenital / complications
  • Heart Defects, Congenital / surgery
  • Humans
  • Immunoenzyme Techniques
  • Immunohistochemistry
  • Polymerase Chain Reaction

Substances

  • Antibodies, Bacterial