A new tissue adhesive for laceration repair in children

J Pediatr. 1998 Jun;132(6):1067-70. doi: 10.1016/s0022-3476(98)70415-9.


To determine the effectiveness of a new tissue adhesive, 2-Octylcyanoacrylate (2-OCA), for laceration repair, 83 children presenting to T.C. Thompson Children's Hospital Emergency Department with lacerations meeting eligibility requirements between February and June 1996 were randomized to receive 2-OCA or nonabsorbable sutures/staples. The length of time for repair was recorded. The length of time for laceration repair was decreased (2.9 minutes 2-OCA vs 5.8 minutes suture/staple; p < 0.001), the parents' assessment of the pain felt by their children in the 2-OCA group was less, and the wounds closed with tissue adhesive had slightly lower cosmesis scores. 2-OCA is an acceptable alternative to conventional methods of wound repair with comparable cosmetic outcome.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child, Preschool
  • Cyanoacrylates*
  • Emergency Treatment
  • Female
  • Humans
  • Male
  • Pain Measurement
  • Surgical Stapling
  • Suture Techniques
  • Time Factors
  • Tissue Adhesives*
  • Wound Healing
  • Wounds, Penetrating / therapy*


  • Cyanoacrylates
  • Tissue Adhesives
  • octyl 2-cyanoacrylate