Some properties of a soluble methane mono-oxygenase from Methylococcus capsulatus strain Bath

Biochem J. 1976 Aug 1;157(2):495-7. doi: 10.1042/bj1570495.


Soluble extracts of Methylococcus capsulatus (Bath), obtained by centrifugation of crude extracts at 160000g for 1h, catalyse the NAD(P)H- and O2-dependent disappearance of bromomethane, and also the formation of methanol from methane. Soluble methane mono-oxygenase is not inhibited by chelating agents or by most electron-transport inhibitors, and is a multicomponent enzyme.

MeSH terms

  • Electron Transport
  • Gram-Negative Aerobic Bacteria / enzymology*
  • Methane / analogs & derivatives
  • Methane / metabolism
  • Methanol / metabolism
  • Oxygenases / antagonists & inhibitors
  • Oxygenases / metabolism*


  • Oxygenases
  • Methane
  • Methanol