Use of the logistic model in retrospective studies

Biometrics. 1976 Sep;32(3):599-606.


A logistic regression model is used to study the association between a dichotomous exposure variable and a disease. The method takes into account factors that may confound the association and leads to a quantitative study of the influence of factors which are related to the strength of the association. Special results are given for matched pair data. A case-control study relating post-menopausal estrogen use and endometrial cancer provides illustration.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Biometry*
  • Disease / etiology*
  • Estrogens / therapeutic use
  • Female
  • Humans
  • Hypertension / complications
  • Menopause
  • Models, Biological*
  • Obesity / complications
  • Retrospective Studies*
  • Statistics as Topic*
  • Uterine Neoplasms / diagnosis
  • Uterine Neoplasms / etiology


  • Estrogens