Membrane fusion: all done with SNAREpins?

Curr Biol. 1998 May 21;8(11):R390-3. doi: 10.1016/s0960-9822(98)70245-3.


SNARE proteins are sufficient to fuse artificial membranes together. In the cell, vesicle transport may rely on fusion mediated by interaction between vesicle (v) and target (t) SNAREs, whereas the homotypic fusion of organelle biogenesis may be mediated by t-SNARE-t-SNARE interaction.

Publication types

  • Review

MeSH terms

  • Carrier Proteins / physiology
  • Macromolecular Substances
  • Membrane Fusion / physiology*
  • Membrane Proteins / chemistry
  • Membrane Proteins / physiology*
  • Models, Biological
  • N-Ethylmaleimide-Sensitive Proteins
  • SNARE Proteins
  • Saccharomyces cerevisiae / physiology
  • Vesicular Transport Proteins*


  • Carrier Proteins
  • Macromolecular Substances
  • Membrane Proteins
  • SNARE Proteins
  • Vesicular Transport Proteins
  • N-Ethylmaleimide-Sensitive Proteins