Visual improvement during octreotide therapy in a case of episellar meningioma

Clin Neurol Neurosurg. 1998 Mar;100(1):40-3. doi: 10.1016/s0303-8467(97)00110-8.


Meningiomas of the tuberculum sellae can induce compression of the optic tract. We report the case of a 54-year-old female patient affected by a suspected pituitary macroadenoma with severe visual field defects, who experienced a significant clinical and visual improvement during short-term octreotide therapy, contrasting with the lack of neuroradiological evidence for tumor shrinkage. The patient subsequently underwent transcranial surgery with a final diagnosis of meningioma. The putative mechanisms of visual improvement during octreotide therapy are discussed.

Publication types

  • Case Reports

MeSH terms

  • Adenoma / diagnosis*
  • Antineoplastic Agents, Hormonal / therapeutic use*
  • Diagnosis, Differential
  • Female
  • Humans
  • Meningeal Neoplasms / complications
  • Meningeal Neoplasms / diagnosis
  • Meningeal Neoplasms / drug therapy*
  • Meningioma / complications
  • Meningioma / diagnosis
  • Meningioma / drug therapy*
  • Middle Aged
  • Octreotide / therapeutic use*
  • Pituitary Neoplasms / diagnosis*
  • Treatment Outcome
  • Vision Disorders / drug therapy*
  • Vision Disorders / etiology


  • Antineoplastic Agents, Hormonal
  • Octreotide