Diphenylhydantoin-induced hepatitis: a case report

Hepatogastroenterology. 1998 Mar-Apr;45(20):411-4.

Abstract

This case report is of a 25-year old man with severe diphenylhydantoin-induced hepatitis, fever, rash and generalized lymphadenopathy. Hepatic histology and lymphocyte transformation tests strongly supported the diagnosis. He made an uneventful recovery with supportive therapy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anticonvulsants / adverse effects*
  • Anticonvulsants / therapeutic use
  • Chemical and Drug Induced Liver Injury / etiology*
  • Drug Eruptions / etiology
  • Humans
  • Lymphatic Diseases / chemically induced
  • Male
  • Phenytoin / adverse effects*
  • Phenytoin / therapeutic use
  • Seizures / drug therapy
  • Time Factors

Substances

  • Anticonvulsants
  • Phenytoin