Chromo-domain proteins: linking chromatin structure to epigenetic regulation

Curr Opin Cell Biol. 1998 Jun;10(3):354-60. doi: 10.1016/s0955-0674(98)80011-2.


Chromo-domain proteins appear to be a central component in the epigenetic regulation of heterochromatin function and euchromatic gene expression. The recent discovery of a variety of interacting partners of chromo-domain proteins is yielding new molecular insights into epigenetic regulatory processes acting at the level of higher order chromatin structure.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Chromatin / genetics*
  • Chromosomal Proteins, Non-Histone*
  • Gene Expression Regulation / physiology*
  • Humans
  • Molecular Sequence Data
  • Repressor Proteins*


  • Chromatin
  • Chromosomal Proteins, Non-Histone
  • Repressor Proteins