American cutaneous leishmaniasis due to Leishmania (Viannia) guyanensis as an initial clinical presentation of human immunodeficiency virus infection

J Eur Acad Dermatol Venereol. 1998 May;10(3):214-7. doi: 10.1016/s0926-9959(98)00011-7.


The authors present the first report of Leishmania (Viannia) guyanensis (L.(V.) guyanenesis) associated with human immunodeficiency virus (HIV) in a Brazilian heterosexual man. It is also the first case of HIV infection associated with American cutaneous leishmaniasis in Brazilian Western Amazonia. The patient had cutaneous and mucous lesions with a negative Montenegro skin test. Histopathology showed large numbers of amastigotes, even in a lesion which had clinically healed. L.(V.) guyanenesis was typed by an immunoenzymatic technique. Various therapies were attempted, but the patient relapsed after each episode of treatment.

Publication types

  • Case Reports

MeSH terms

  • AIDS-Related Opportunistic Infections / diagnosis*
  • AIDS-Related Opportunistic Infections / parasitology
  • AIDS-Related Opportunistic Infections / pathology
  • Adult
  • Animals
  • Brazil
  • Diagnosis, Differential
  • Humans
  • Leishmania guyanensis / isolation & purification*
  • Leishmaniasis, Mucocutaneous / diagnosis*
  • Leishmaniasis, Mucocutaneous / parasitology
  • Leishmaniasis, Mucocutaneous / pathology
  • Male
  • Nose Diseases / diagnosis
  • Nose Diseases / parasitology*