New ceramide from marine sponge Haliclona koremella and related compounds as antifouling substances against macroalgae

T Hattori; K Adachi; Y Shizuri

doi:10.1021/np970527y

New ceramide from marine sponge Haliclona koremella and related compounds as antifouling substances against macroalgae

J Nat Prod. 1998 Jun 26;61(6):823-6. doi: 10.1021/np970527y.

Authors

T Hattori¹, K Adachi, Y Shizuri

Affiliation

¹ Marine Biotechnology Institute, Shimizu Laboratories, 1900 Sodeshi, Shimizu, Shizuoka 424, Japan. hatto@shimizu.mbio.co.jp

PMID: 9644076
DOI: 10.1021/np970527y

Abstract

A new ceramide N-docosanoyl-d-erythro-(2S, 3R)-16-methyl-heptadecasphing-4(E)-enine (C22 ceramide) was isolated from the marine sponge Haliclona koremella as an antifouling substance against macroalgae. The structure of this substance was elucidated by spectral means. Antifouling activity of several related compounds was also examined.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Ceramides / isolation & purification*
Ceramides / pharmacology
Eukaryota / drug effects*
Eukaryota / genetics
Magnetic Resonance Spectroscopy
Mass Spectrometry
Porifera / chemistry*
Spectrophotometry, Infrared
Spectrophotometry, Ultraviolet

Substances

Ceramides
N-docosanoyl-16-methylheptadecasphing-4-enine