Low-level viremia and intracellular expression of hepatitis B surface antigen (HBsAg) in HBsAg carriers with concurrent hepatitis C virus infection

J Clin Microbiol. 1998 Jul;36(7):2084-6. doi: 10.1128/JCM.36.7.2084-2086.1998.


Assays of hepatitis B virus (HBV) replication and antigen expression in HBV surface antigen (HBsAg) carriers with concurrent hepatitis C or D virus (HCV or HDV) infection revealed that HCV and HDV can suppress HBV replication but that HCV also substantially suppresses HBV surface protein expression. HBsAg carriers with concurrent HCV infection thus have low-level viremia and intracellular HBsAg.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carrier State / virology*
  • Female
  • Hepatitis B / complications*
  • Hepatitis B / virology*
  • Hepatitis B Surface Antigens / analysis*
  • Hepatitis B Surface Antigens / blood
  • Hepatitis B virus / genetics
  • Hepatitis B virus / physiology*
  • Hepatitis C / complications*
  • Hepatitis D / complications
  • Humans
  • Male
  • Radioimmunoassay
  • Viremia*
  • Virus Replication


  • Hepatitis B Surface Antigens