Ion channels: a first view of K+ channels in atomic glory

Curr Biol. 1998 Jun 18;8(13):R450-2. doi: 10.1016/s0960-9822(98)70290-8.


Crystal structures have been solved for the transbilayer pore domain of a bacterial K+ channel and the tetramerisation domain of voltage-gated K+ channel. These provide our first real structural insights into possible mechanisms of ion selectivity and permeation for K+ channels.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Bacterial Proteins*
  • Crystallography, X-Ray
  • Drosophila
  • Drosophila Proteins
  • Models, Molecular
  • Potassium Channels / chemistry*
  • Protein Structure, Secondary
  • Protein Structure, Tertiary
  • Shaker Superfamily of Potassium Channels
  • Streptomyces


  • Bacterial Proteins
  • Drosophila Proteins
  • Potassium Channels
  • Sh protein, Drosophila
  • Shaker Superfamily of Potassium Channels
  • prokaryotic potassium channel