Meconium-stained amniotic fluid and the meconium aspiration syndrome. An update

Pediatr Clin North Am. 1998 Jun;45(3):511-29. doi: 10.1016/s0031-3955(05)70025-0.


Over the past 5 years, increasing understanding about the pathophysiology of meconium-stained amniotic fluid (MSAF) and the meconium aspiration syndrome (MAS) has occurred. Many new therapies are being used in an attempt to prevent MAS and to treat the disorder. The authors review the current status of knowledge concerning the MSAF and MAS and management of these entities.

Publication types

  • Review

MeSH terms

  • Amniotic Fluid* / chemistry
  • Chorioamnionitis / etiology
  • Female
  • Humans
  • Infant, Newborn
  • Inflammation
  • Intensive Care, Neonatal / methods*
  • Meconium Aspiration Syndrome* / diagnosis
  • Meconium Aspiration Syndrome* / etiology
  • Meconium Aspiration Syndrome* / physiopathology
  • Meconium Aspiration Syndrome* / therapy
  • Meconium* / chemistry
  • Pregnancy
  • Pregnancy Outcome
  • Respiratory Distress Syndrome, Newborn / etiology