Molecular recapitulation: the growth of the vertebrate retina
- PMID: 9654012
Molecular recapitulation: the growth of the vertebrate retina
Abstract
In postembryonic lower vertebrates, the ciliary marginal zone (CMZ) of the retina is a continuously growing zone in the central nervous system. By studying the cellular and molecular biology of the cells in this region, we have discovered that the CMZ can be divided into several zones, from peripheral to central, which reflect different stages of development of retinal stem cells. Based on the behavior of the cells and on the genes expressed in different regions, we propose here that cellular development in the CMZ recapitulates in space what happens in embryonic retinal development in time.
Similar articles
-
Canonical Wnt signaling controls proliferation of retinal stem/progenitor cells in postembryonic Xenopus eyes.Stem Cells. 2008 Aug;26(8):2063-74. doi: 10.1634/stemcells.2007-0900. Epub 2008 Jun 12. Stem Cells. 2008. PMID: 18556512
-
Multipotential stem cells and progenitors in the vertebrate retina.J Neurobiol. 1998 Aug;36(2):206-20. J Neurobiol. 1998. PMID: 9712305 Review.
-
Genetic dissection of the zebrafish retinal stem-cell compartment.Dev Biol. 2005 May 1;281(1):53-65. doi: 10.1016/j.ydbio.2005.02.010. Dev Biol. 2005. PMID: 15848388
-
The genetic sequence of retinal development in the ciliary margin of the Xenopus eye.Dev Biol. 1998 Jul 15;199(2):185-200. doi: 10.1006/dbio.1998.8939. Dev Biol. 1998. PMID: 9698439
-
Retinal stem cells in vertebrates.Bioessays. 2000 Aug;22(8):685-8. doi: 10.1002/1521-1878(200008)22:8<685::AID-BIES1>3.0.CO;2-C. Bioessays. 2000. PMID: 10918298 Review.
Cited by
-
Unliganded thyroid hormone receptor is essential for Xenopus laevis eye development.EMBO J. 2006 Oct 18;25(20):4943-51. doi: 10.1038/sj.emboj.7601356. Epub 2006 Sep 28. EMBO J. 2006. PMID: 17006540 Free PMC article.
-
Müller glia: Stem cells for generation and regeneration of retinal neurons in teleost fish.Prog Retin Eye Res. 2014 May;40:94-123. doi: 10.1016/j.preteyeres.2013.12.007. Epub 2014 Jan 8. Prog Retin Eye Res. 2014. PMID: 24412518 Free PMC article. Review.
-
Single-cell analyses reveal transient retinal progenitor cells in the ciliary margin of developing human retina.Nat Commun. 2024 Apr 26;15(1):3567. doi: 10.1038/s41467-024-47933-x. Nat Commun. 2024. PMID: 38670973 Free PMC article.
-
A Comparison of the Primary Sensory Neurons Used in Olfaction and Vision.Front Cell Neurosci. 2020 Nov 5;14:595523. doi: 10.3389/fncel.2020.595523. eCollection 2020. Front Cell Neurosci. 2020. PMID: 33250719 Free PMC article. Review.
-
What drives cell morphogenesis: a look inside the vertebrate photoreceptor.Dev Dyn. 2009 Sep;238(9):2115-38. doi: 10.1002/dvdy.22010. Dev Dyn. 2009. PMID: 19582864 Free PMC article. Review.