Molecular cloning of a gene encoding phospholipase D from the pathogenic and dimorphic fungus, Candida albicans

Biochim Biophys Acta. 1998 Jul 9;1398(3):359-64. doi: 10.1016/s0167-4781(98)00067-0.

Abstract

A phospholipase D gene (CaPLD) has been cloned from the Candida albicans genomic DNA library. The CaPLD is a member of a highly conserved gene family of PLD and has the highest homology to Saccharomyces cerevisiae PLD (SPO14) with an overall homology of 42%. Phylogenetic analysis indicated that fungus PLDs including CaPLD composed one of the three clusters of PLD genes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Candida albicans / enzymology*
  • Candida albicans / genetics
  • Cloning, Molecular
  • DNA, Fungal
  • Humans
  • Molecular Sequence Data
  • Phospholipase D / classification
  • Phospholipase D / genetics*
  • Sequence Homology, Amino Acid

Substances

  • DNA, Fungal
  • Phospholipase D

Associated data

  • GENBANK/AB010810