[Therapy of articular and periarticular pain with local anesthetics (neural therapy of Huneke). Long and short term results]

Minerva Anestesiol. 1998 Jan-Feb;64(1-2):35-43.
[Article in Italian]


Objective: Assessment of the outcomes on the articular and periarticular pain of the knee, by a reflexotherapy with local anesthetics, denominated also neuraltherapy.

Experimental design: Retrospective observational study with 3 years' follow-up.

Environment: An Ambulatory Center for Pain Management.

Patients: All the patients (N = 115) with knee pain treated with neuraltherapy in the period 1982-31 August 1996 (retired patients 2, mean age 68 +/- 15.2 years in the remaining).

Interventions: The employed reflexotherapy, denominated also neuraltherapy by Huneke, uses a local anesthetic (prevalently lidocaine) in 0.5-1% concentration and small quantity (0.5-1 ml for point) on tender/trigger and/or acupuncture points, as well as in anatomical structures like articulations, nerves, arteries or veins. The number of sessions has been of 7.03 +/- 3.3.

Outcome measures: Outcomes are evaluated in terms of percentage subjective improvement of the pain at the end of the therapy and at 1-3-6 months, 1-2-3 years, and then divided in 5 groups (no improvement-fair-good-very good-excellent).

Results: At the end of the therapy the improven cases were the 91.2%, the 83.7% at 1 month, the 64.6% at 3 months, the 41.3% at 6 months, the 22.5% at 1 year, the 12.1% at 2 years and the 7.9% at 3 years.

Conclusions: These outcomes suggest a good effectiveness of this treatment in the painful diseases of the knee, but further randomised double-blind trials are necessary.

Publication types

  • Clinical Trial
  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Anesthetics, Local / administration & dosage
  • Anesthetics, Local / therapeutic use*
  • Arthralgia / drug therapy*
  • Cartilage, Articular*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Time Factors


  • Anesthetics, Local