Anterior capsule contraction and intraocular lens dislocation after implant surgery in eyes with retinitis pigmentosa

Ophthalmology. 1998 Jul;105(7):1239-43. doi: 10.1016/S0161-6420(98)97028-2.


Objective: The purpose of the study was to investigate the extent of anterior capsule contraction, intraocular lens (IOL) decentration, and tilt after implant surgery in eyes with retinitis pigmentosa (RP).

Design: A case-control study.

Participants: Forty-seven eyes from 47 patients with typical RP and 47 control eyes from 47 age-matched healthy patients were studied.

Intervention: Phacoemulsification surgery with polymethylmethacrylate IOL implantation with continuous curvilinear capsulorrhexis was performed.

Main outcome measures: The area of the anterior capsule opening obtained with capsulorrhexis and the amount of the decentration and tilt of the IOL were measured using a Scheimpflug photography system at 1 week and 1, 3, 6, 9, and 12 months after surgery.

Results: The mean area in the RP group was found to be significantly smaller than that in the control group at 1 month after surgery and later (P < 0.0001). The percent area reduction in the RP group at 6 months was 45.2 +/- 25.8% and 4.6 +/- 13.5% in the control group. Both the decentration length and tilt angle were also greater in the RP group than in the control group. Fourteen (29.8%) of the 47 RP eyes had undergone a neodymium:YAG (Nd:YAG) laser anterior capsulotomy at 12 months after surgery, whereas none of the control eyes had undergone an Nd:YAG.

Conclusions: Anterior capsule contraction in the RP eyes was more extensive than in the control eyes, leading to a high Nd:YAG laser anterior capsulotomy rate. Both lens decentration and tilt also were greater in the RP eyes than in the control eyes.

Publication types

  • Comparative Study

MeSH terms

  • Anterior Chamber
  • Case-Control Studies
  • Contracture / etiology*
  • Contracture / pathology
  • Female
  • Foreign-Body Migration / etiology*
  • Foreign-Body Migration / pathology
  • Humans
  • Laser Therapy
  • Lens Capsule, Crystalline / pathology*
  • Lens Capsule, Crystalline / surgery
  • Lens Implantation, Intraocular*
  • Lenses, Intraocular*
  • Male
  • Middle Aged
  • Phacoemulsification
  • Polymethyl Methacrylate
  • Postoperative Complications*
  • Prospective Studies
  • Retinitis Pigmentosa / complications*


  • Polymethyl Methacrylate