Ribozymes: the hammerhead swings into action

Curr Biol. 1998 Jul 2;8(14):R495-7. doi: 10.1016/s0960-9822(98)70316-1.


A new crystal structure of a modified hammerhead ribozyme reveals an intermediate conformation that may explain discrepancies between previous structures and the required orientation of the labile bond in the ribozyme's active site.

Publication types

  • Review

MeSH terms

  • Base Sequence
  • Binding Sites
  • Models, Molecular
  • Nucleic Acid Conformation*
  • RNA, Catalytic / chemistry*
  • RNA, Catalytic / metabolism*


  • RNA, Catalytic