A randomized study comparing manual lymph drainage with sequential pneumatic compression for treatment of postoperative arm lymphedema

Lymphology. 1998 Jun;31(2):56-64.


We compared manual lymph drainage (MLD) with sequential pneumatic compression (SPC) for treatment of unilateral arm lymphedema in 28 women previously treated for breast cancer. After 2 weeks of therapy with a standard compression sleeve (Part I) with maintenance of a steady arm volume, each patient was randomly assigned to either one of two treatment regimens (Part II). MLD was performed according to the Vodder technique for 45 min/day and SPC was performed with a pressure of 40-60 mmHg for 2 hours/day. Both treatments were carried out for 2 weeks. Arm volume was measured by water displacement. Arm mobility, strength, and subjective assessments were also determined. Lymphedema was reduced by 49 ml (7% reduction) (p = 0.01) in the total group during Part I. During Part II, the MLD group decreased by 75 ml (15% reduction) (p < 0.001) and the SPC group by 28 ml (7% reduction) (p = 0.03). The total group reported a decrease of tension (p = 0.004) and heaviness (p = 0.01) during Part I. During Part II, only the MLD group reported a further decrease of tension (p = 0.01) and heaviness (p = 0.008). MLD and SPC each significantly decreased arm volume but no significant difference was detected between the two treatment methods.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Arm* / pathology
  • Arm* / physiology
  • Bandages
  • Drainage / methods*
  • Female
  • Humans
  • Isometric Contraction
  • Lymphedema / pathology
  • Lymphedema / physiopathology
  • Lymphedema / therapy*
  • Mastectomy / adverse effects*
  • Middle Aged
  • Movement
  • Pain Measurement
  • Pressure*
  • Prospective Studies
  • Statistics, Nonparametric