Dead box for the living

J Pathol. 1998 Apr;184(4):345-7. doi: 10.1002/(SICI)1096-9896(199804)184:4<345::AID-PATH1243>3.0.CO;2-6.


Members of a large family of proteins, called the DEAD box family, are ribonucleic acid binding proteins with ATPase activity. Recent investigations into the developmentally and cell type-specific expression patterns of one family member, p68 RNA helicase, suggest that this protein might play a role in organ differentiation and/or maturation, and that its expression is subject to complex regulation.

Publication types

  • Editorial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bacterial Proteins / genetics*
  • Bacterial Proteins / physiology
  • Gene Expression Regulation, Enzymologic
  • Mice
  • RNA Helicases*
  • RNA Nucleotidyltransferases / genetics*
  • RNA Nucleotidyltransferases / physiology


  • Bacterial Proteins
  • RNA Nucleotidyltransferases
  • RNA Helicases