Low field T1rho imaging of myositis

Magn Reson Imaging. 1998 May;16(4):385-91. doi: 10.1016/s0730-725x(98)00004-6.


The purpose of this study was to evaluate 1/T1rho in relation to 1/T1 and 1/T2 in characterizing normal and diseased muscle. We measured the muscle relaxation rates 1/T1 and 1/T2 at 0.1 T and 1/T1rho at on-resonance locking fields B1 between 10 and 160 microT in myositis patients and normal volunteers. 1/T2 and 1/T1rho of muscle were lower in the patients than in the volunteers, whereas there was no difference in the 1/T1 values. The lower relaxation rates 1/T2 and 1/T1rho in the diseased muscle may be due to fat and connective tissue infiltrations and edema. 1/T1rho contrast between muscle and subcutaneous fat was higher than 1/T2 and 1/T1 contrast. This may be explained by the different B1 dispersion behavior of these two tissue types. 1/T1rho of fat is B1 field independent, whereas 1/T1rho of muscle decreases clearly with increasing B1 field. In conclusion, 1/T1rho provides a useful tool in manipulating contrast in magnetic resonance imaging of diseased muscle.

Publication types

  • Comparative Study

MeSH terms

  • Adipose Tissue / pathology
  • Aged
  • Connective Tissue / pathology
  • Edema / diagnosis
  • Female
  • Humans
  • Magnetic Resonance Imaging*
  • Male
  • Middle Aged
  • Muscle Relaxation
  • Muscle, Skeletal / pathology*
  • Muscle, Skeletal / physiopathology
  • Myositis / diagnosis*
  • Myositis / physiopathology