The architectural organization and mechanistic function of group II intron structural elements

Curr Opin Struct Biol. 1998 Jun;8(3):301-8. doi: 10.1016/s0959-440x(98)80062-6.


Group II introns are large, self-splicing RNAs and mobile genetic elements that provide good model systems for studies of RNA folding. The structures and mechanistic functions of individual domains are being elucidated, and long-range tertiary interactions between the domains are being identified, thus helping to define the three-dimensional architecture of the intron.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Base Sequence
  • Conserved Sequence
  • Introns*
  • Molecular Sequence Data
  • Nucleic Acid Conformation*
  • RNA / chemistry*
  • RNA / genetics*
  • RNA Splicing


  • RNA