Systemic Fusarium oxysporum infection in an immunocompetent patient with an adult respiratory distress syndrome (ARDS) and extracorporal membrane oxygenation (ECMO)

Mycoses. Mar-Apr 1998;41(3-4):109-11. doi: 10.1111/j.1439-0507.1998.tb00310.x.

Abstract

We report a case of disseminated fusariosis in a 42-year-old patient with adult respiratory distress syndrome (ARDS) and extracorporal membrane oxygenation (ECMO), but without definite immunosuppression. Fusarium oxysporum was isolated from a bronchial lavage taken 6 days ante mortem. Despite antifungal treatment with amphotericin B and flucytosine the patient died in septic multiorgan failure. A post-mortem examination was performed. The patient's liver was found to contain fungus cells and F. oxysporum could be cultured from ascites.

MeSH terms

  • Adult
  • Amphotericin B / therapeutic use
  • Antifungal Agents / therapeutic use
  • Extracorporeal Membrane Oxygenation*
  • Fusarium*
  • Humans
  • Immunocompetence
  • Liver Diseases / microbiology
  • Lung Diseases, Fungal / microbiology
  • Male
  • Mycoses / complications*
  • Mycoses / drug therapy
  • Mycoses / mortality
  • Respiratory Distress Syndrome, Adult / complications*
  • Respiratory Distress Syndrome, Adult / mortality

Substances

  • Antifungal Agents
  • Amphotericin B