Do loxapine plus cyproheptadine make an atypical antipsychotic? PET analysis of their dopamine D2 and serotonin2 receptor occupancy

Arch Gen Psychiatry. 1998 Jul;55(7):666-8. doi: 10.1001/archpsyc.55.7.666.
No abstract available

Publication types

  • Letter

MeSH terms

  • Antipsychotic Agents / pharmacokinetics*
  • Antipsychotic Agents / pharmacology
  • Antipsychotic Agents / therapeutic use*
  • Cyproheptadine / pharmacokinetics*
  • Cyproheptadine / pharmacology
  • Cyproheptadine / therapeutic use*
  • Drug Administration Schedule
  • Drug Therapy, Combination
  • Humans
  • Loxapine / pharmacokinetics*
  • Loxapine / pharmacology
  • Loxapine / therapeutic use*
  • Receptors, Dopamine D2 / drug effects
  • Receptors, Dopamine D2 / metabolism*
  • Receptors, Serotonin / drug effects
  • Receptors, Serotonin / metabolism*
  • Schizophrenia / diagnostic imaging
  • Schizophrenia / drug therapy*
  • Schizophrenia / metabolism
  • Serotonin Antagonists / pharmacokinetics*
  • Serotonin Antagonists / pharmacology
  • Serotonin Antagonists / therapeutic use*
  • Tomography, Emission-Computed*

Substances

  • Antipsychotic Agents
  • Receptors, Dopamine D2
  • Receptors, Serotonin
  • Serotonin Antagonists
  • Cyproheptadine
  • Loxapine