What Happens to Bacterial Pathogens in Vivo?

Trends Microbiol. 1998 Jun;6(6):239-43. doi: 10.1016/s0966-842x(98)01250-5.


Most of our current knowledge about the molecular determinants of bacterial pathogenicity comes from studies with cultures in vitro. However, interest is increasing in bacterial behaviour in the complex and ever-changing environment of the infected host. New methods are revealing how bacteria behave in their hosts, providing many surprises and indicating how much of the subject remains unexplored.

Publication types

  • Review

MeSH terms

  • Animals
  • Bacteria / genetics
  • Bacteria / growth & development
  • Bacteria / pathogenicity*
  • Bacterial Physiological Phenomena
  • Bacteriological Techniques
  • Humans
  • Virulence