The purpose of this study was to examine the association of beliefs and attitude related to smoking and smoking behavior among school dropouts in a national sample (weighted N = 492,352). The self-reported smoking rate for school dropouts was 58.3%. Those who were most positive about smoking (such as smoking helps people reduce stress and relax, reduce boredom) were more likely to be smokers (p < .05). Smoking programs targeting this population should provide coping skills and an environment with options for relaxing, managing stress, and safe weight control.