Characteristics of basolateral amygdala neuronal firing on a spatial memory task involving differential reward

Behav Neurosci. 1998 Jun;112(3):554-70. doi: 10.1037//0735-7044.112.3.554.


Previous research has shown that spatial, movement, and reward information is integrated within the ventral striatum (VS). The present study examined the possible contribution of the basolateral nuclei of the amygdala (BLA) to this interaction by examining behavioral correlates of BLA neurons while rats performed multiple memory trials on an 8-arm radial maze. Alternate arms consistently held 1 of 2 different amounts of reward. Recorded cells were correlated with motion, auditory input, space, and reward acquisition. Reward-related units were found that anticipated reward encounter, that responded during reward consumption, and that differentiated between high and low reward magnitude. This is consistent with the hypothesis that BLA neurons may provide the VS with reward-related information that could then be integrated with spatial information to ultimately affect goal-directed behavior.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amygdala / physiology*
  • Analysis of Variance
  • Animals
  • Appetitive Behavior / physiology
  • Cacao
  • Choice Behavior / physiology
  • Cues*
  • Evoked Potentials
  • Male
  • Maze Learning / physiology*
  • Memory / physiology*
  • Neural Inhibition / physiology
  • Orientation / physiology
  • Rats
  • Rats, Inbred Strains
  • Reward*
  • Time Factors